At 19:15 on July 8th, 2008 points
leveraging finally realized the ultimate upset, a bunch of work on hand did not touch a tap, greeting colleagues hate, hate the leaders care, hate the phone rings .... .. After the return of reason do not want to go home or disgraced in the inside, but no longer surprised to find that even the strength to back - home, Chennai Ruohe word is really a bother. I remember the weekend that the three cis mother said proudly to the president: too many gloomy state of madness and the aching organ. always put their own sorrows and joys, and hopes to give such and such an easy life and death does not care about their people, and is doomed to heartache, and doomed to despair and tragedy.
I tried my best to cry, even if the single remaining years even if the helpless larvae life, I do not go to pray, do not always find a missing person. Although I can hear the phone ring will irritable will be playing timid, but the phone is my work, the right to contact friends outside of work to me, it is my duty available to confirm my existence and security, although extremely Chicks, though at a glance. remember that Lu Xun words: even if the light is also a small stream of clear light and sincere thank you for giving me the reasons for existence.
CP even recall the boss gave me the first lesson on the workplace, Why change clothes? because of the need to prove that you returned home ~ ~
Tuesday, February 22, 2011
Monday, February 21, 2011
I nearly died infusion, to draw attention to the left g (Levofloxacin)
1, yesterday morning, go to the hospital transfusion, transmission on the left g (levofloxacin injection) in less than a few minutes, his voice tight, hold back hair, until all the teeth are numb. The symptoms are similar to pipe a little zip lock. I wanted to teeth, so that rattan cane to me a bit slow the flow, regardless of use. I said to Heding Hong efficacy did not so quickly, right? then quickly mute my voice out, and vomiting. Two girlfriends emergency doctor to the dressing and rapidly injected with allergy.
2, the doctor said then save a minute later, my throat will be completely closed, must directly cut, intubation breathing. There is also a land approach to the animals injected with about dozens of the huge number of needle directly to the neck and tie a big hole. breathes breathing.
3, the speech difficulties, I get the usual low-key deep nonsense, just with open tears bark, and the innocent and helpless, pathetic, sort of a small two eyes, separated glasses, nostalgia, looking at the world. think of the money not spent finished, people do not love enough, the sadness of parting, with mixed feelings. < br> 4, hula family came to the hospital. Our family Daniu rushing tears. Erniu indifferent to our house (since she can never expect to eat great dragon (Wing) shrimp).
5, yesterday afternoon and evening, to drink cup of warm boiled water reached nearly to eat watermelon two, the mouth piece with a dozen VC buccal tablets. crazy sweating, urinating on the toilet an average of five minutes once. finally left grams (levofloxacin injection) is scheduled to be almost the same.
6, now no longer face pale, Yin-Tang no longer blue, his voice has been able to speak. Daniu said: Silent cute, now you're restored to the world's most annoying bitch. is certainly not an injection. can not resolve injection infusion.
2, not because hospitals everywhere when you are president of the iron sister, Director of Nursing you have no big problems go to the hospital to play. accounting for the mental hospital cheap no longer there. more not to lie and they want to talk to his girlfriend on an intravenous drip.
3, left millions of caution grams (Levofloxacin Hydrochloride Injection) and all easy to allergy medications. my daughter was allergic to penicillin are also shock . if you feel unwell, do not hesitate, do not observe an immediate pull fluid.
4, said her daughter went to the hospital to see me cry I think the way: my mom giant strong man, and never trouble people. certainly only for his family to die, son wants his parents away, but Mom did not know women want to study. So little friends to remind you learn every day, do not let my parents worry.
Here is what I left in the online search grams of allergy cases reflect:
of : pete2188 filing date :2006-7-3 23:53:37
girlfriend a few days ago with fever fever of 39 degrees, go to Shanghai Punan hospital emergency room doctor on duty for a blood test, then decided to give fluids, we remind penicillin allergy The doctor said that he cephalosporins? We asked cephalosporins penicillin allergy can play it? decided to play left-grams, 0.3g (5% glucose 500ml) * 3 days, things started from the left-grams. infusion also reclaim heat for two days, during accompanied by dizziness, palpitation, suffocation, cold sweat, excitement, headache, insomnia, nausea, skin rash (purpura, systemic showed migratory pain), consult a doctor, saying that there is a cooling process. to continue treatment. end of the day infusion, heat has not yet retired, also increased the diarrhea, the body was becoming more and more migratory severe pain, allergic purpura red dot increases. can be said that all the side effects of left grams have emerged. I really do not know the manufacturer and the hospital how the services for patients.
We hope that we note that levofloxacin with hydrochloric acid when the alert to avoid the physical suffering of more pain ..
: pete2188 Reply Date :2006 -7-323: 54:00
Here is another User's Friendly reminder: the left g (Levofloxacin Hydrochloride Injection)
Indications:
This product applies to the following sensitive bacteria in severe infections: 1. Respiratory infections: acute bronchitis, acute exacerbation of chronic bronchitis, diffuse bronchitis, bronchiectasis with infection, pneumonia, tonsillitis (peritonsillar abscess). 2. Urinary tract infections: pyelonephritis, complicated urinary tract infections 3.. reproductive system infections: acute prostatitis, acute inflammation epididymis, uterine infection, uterine annex inflammation, pelvic inflammatory disease (suspected anaerobic infections can be combined with metronidazole). 4. skin and soft tissue infections: infectious pus blister disease, cellulitis, lymphatic (node) inflammation, subcutaneous abscess, anal abscess. 5. gastro-intestinal infections: bacillary dysentery, infectious enteritis, salmonella enteritis, typhoid and paratyphoid. 6. sepsis, granulocyte cells decreased and immunocompromised patients with various infections. 7. Other infections: mastitis, trauma, burns and surgical wound infection, abdominal infection (combined with metronidazole if necessary), cholecystitis, cholangitis, bone and joint infections and ENT infections.
��Usage and Dosage��:
intravenous drip: Adult daily 0.4g, 2 times intravenous infusion. pathogen of severe infection and is less sensitive to the chemicals (such as Pseudomonas aeruginosa Aeromonas), maximum daily dose can be increased to 0.6g, intravenous infusion of 2 times.
grams for the left, to note that its side effects. Of course, all the drugs will have side effects.
from the north Medical Hospitals Allergy symptoms will not occur. However, to avoid the occurrence of allergic symptoms, requirements: the infusion time, the slow trickle. usual dose vials, the input of not less than one hours time.
this knowledge because of the recent their loved ones, lost in half an hour left over .24 grams or more hours there than that, in addition to all the allergy symptoms of vertigo: First, rapid heart rate, chest tightness, shortness of breath, nausea, headache, high fever does not retreat excited can not sleep, then whole body and face skin rash and erythema, it is painful
of: pete2188 Reply Date :2006-7-3 23:57:00
Chief Medical Network>> Magazine>> China Modern Clinical Medicine> net Zhou Hui 2006-2-23 21:39:03 Journal of Modern Clinical Medicine January 2006 Volume 4 No. 2
Keywords: Levofloxacin
Abstract In this paper, recent years on levofloxacin (LVFX) documentation of adverse reactions to summarize, the main side effects include gastrointestinal reactions, allergic reactions, and central nervous system reactions. prompted the clinical use of the drug when in the stricter control over their indications, take the right to use, and careful combination to avoid and reduce adverse reactions.
Key words levofloxacin; adverse reactions
levofloxacin (levofloxacin, LVFX) was first developed in 1994 by the Japanese successfully developed, it is the 3rd generation quinolone antibacterial drug is the racemic ofloxacin enantiomer, the antibacterial spectrum covering gram-positive bacteria, Gram-negative bacteria, anaerobic bacteria, atypical pathogens, and mycobacteria. In vitro antibacterial activity of oxygen 2 times the fluoride Sand Star, D-Body (R-OFLX), 8 ~ 128 times. oral bioavailability, tissue permeability, can be quickly distributed to various organizations, long half-life, 85% through urine excretion. extensive for respiratory, gastroenterology, gynecology, dermatology, surgery and other departments. In this paper, the past 5 years at home and abroad about the adverse effects of levofloxacin appears to summarize the literature data, are summarized below.
1 gastrointestinal reaction
Lv Libo [1] and reported in the treatment of tuberculosis with LVFX injection in 24 patients with varying degrees of side effects: gastrointestinal reactions including 10 cases (41.67%), dizziness, headache in 6 patients (25.00%), pruritus, rash in 5 patients (20.83%), fever, heart palpitations in 2 cases (8.33%), blood urea nitrogen increased 1 (4.17%). All of the above adverse symptoms disappeared after stopping.
2 induced ascites
Wu Xia [2] reported 1 patient was male, 23 years old, a university student. because of headache, sore throat, fever 2 days, on the evening of 21 June 2003 10:00 to treatment. Patients usually physical health, no history of drug allergy . doctors, giving LVFX 200 mg intravenous infusion of 1. 5:00 am the next day, patients with nausea, abdominal distension, abdominal pain, diarrhea, abdominal palpation can be heard, and shifting dullness. B ultrasound diagnosis: ascites (in volume). Disable LVFX. immediate 5% glucose injection 500ml + intravenous dexamethasone 15mg, furosemide 20mg intramuscular injection, intravenous infusion of 20% mannitol 250ml. 8:00 am on day 2, patients with these symptoms, review B- showed no abnormal echo abdominal .2004 Jan. 2, the patient re-infusion LVFX 200mg, once again the above symptoms, B ultrasound diagnosis of ascites. by using the same measures after treatment and gradually returned to normal after the drug is not used, then did not have the symptoms, so consider patients with ascites due to LVFX.
3 allergic reaction allergic drug eruption
3.1 Wu Wei Yan [3] reported one case of female patients suffering from acute purulent tonsillitis intravenous levofloxacin mesylate (Lee Fosun), skin rash during the infusion, the patient in the event of no notice after drug eruption, outdoor activities are more sun, skin rash was worse. of the opinion that the product has a phototoxic reaction (occurring rate of <1%), may result in increased symptoms.
3.2 anaphylactic shock
1 patients with 23-year-old female patient [4], the FDA due to acute gastroenteritis 100ml, dropping speed of 30 drops / min. medicine 5min after the dizziness, limb numbness, followed by symptoms of anaphylactic shock. quickly to anti-shock treatment, about 15min after the above symptoms gradually improved, blood pressure, pulse, respiration returned to normal consciousness turned clear.
3.3 speed hair and delayed type hypersensitivity
Yangming Na [5] reported LVFX induced anaphylactic shock in elderly patients in 2 cases, 1 male patients, aged 82, the patient again in 2 days intravenous infusion of hydrochloric acid LVFX 2min only about the first appears dizziness, sweating, fatigue, hold breath, accompanied by a transient disturbance of consciousness.
LVFX not only led to immediate hypersensitivity, has also led to delayed allergic reactions. Zhuangshu Ping [6] reported that in February 2001, in the sections of their total of 98 patients using the injection LVFX HCl, 5 patients had symptoms of delayed allergic reactions, usually 8 to 12 days treatment appears to have been discontinued and allergy treatment improved. were denied the application in the treatment of other cause during allergy medicine and food, so consider delayed allergic reactions caused by LVFX Department of hydrochloric acid.
3.4 Ashland - Hengnuo syndrome
Liang Pi-xia [7] reported 1 case of female patients, 62 years old, no history of drug allergy, for and excellent surge levels. The next morning there were large migratory joint swelling and pain the whole body, with skin congestion, limited mobility. from the elbow to the knee, wrist, ankle involvement in turn, first right after the left side. At the same time Ministry of right elbow, left knee, right leg and bilateral hip extensor surface of bleeding papules, sizes and irregular, non-itching. with paroxysmal abdominal pain, nausea and vomiting. to the hospital to joint pain of unknown origin, The above symptoms improved, were discharged after 10 days.
3.5 limbs, face, abdomen numbness
m extension from [8] reported 1 case of female patients, aged 28, due to intravenous infusion of upper respiratory tract infection Bupleurum injection, LVFX HCl injection (left grams), medication suddenly felt numbness in patients after 30min, and then the face, abdomen numb, his hands itching, difficult to tolerate, no rash appears. the withdrawal, to give 10% calcium gluconate injection solution, 5% glucose injection, itching stopped after about 10min, then the limbs, face, abdomen numbness have disappeared. The next day, still with the Bupleurum injection fever, and the other using tobramycin injection (properly Xin), until the patients recovered without any adverse reactions occur again. so that the occurrence of allergic reactions are caused by the hydrochloric acid injection LVFX.
of: pete2188 Reply Date :2006-7-4
3.6 off hand-foot skin Chip
Yin Lihua [9] reported 1 case of female patients, aged 70, due to secondary infection of bronchial asthma given aminophylline and LVFX (to Ericsson) 100mg, ivgtt, bid.3 days after the hand-foot skin itching, scaling, that disabled LVFX, 1 week after symptoms of hand-foot skin scaling improved again after 3 months in patients with application of LVFX and aminophylline, 1 day and hand-foot skin itching, scaling, disable LVFX 1 month later, the skin off Chip symptoms.
4 central nervous system reactions, and mental disorders
4.1
epilepsy beam winter months [10] reported one case of female patients, aged 17, in gonadal resection of epidural anesthesia for the prevention of infection, intravenous infusion of LVFX injection 0.4g / d. Enter 100ml 2 days later, the patient suddenly felt the whole body discomfort, facial muscle tension, twitching, eyes forced upward gaze, not closed, sweat more. But the mind clear, accurate answer , denied a history of epilepsy, and other related. examination: P 134 times / min, R 20 times / min, BP 18.0/12.0kPa (135/90mmHg). that disabled LVFX to diazepam (stable), were quiet after treatment sleep, the symptoms disappeared again after .2 h whole body discomfort, mild opisthotonus, again to the stability of symptoms and stable condition. after the switch to penicillin, no recurrence of similar reactions. authors suggest that LVFX inhibits g-aminobutyric acid Therefore, to induce epilepsy. The sudden appearance of patients in the infusion of muscle tension, twitching, eyes forced upward gaze, sweat more, may be caused by epilepsy LVFX. a history of epilepsy should be careful using this, without a history of epilepsy also should be noted.
4.2
Chen Zelian insomnia [11] reported 2 cases of female patients: 1 case of 39-year-old, the other 1 case of 32-year-old, respectively, because of cough, urinary tract infection oral LVFX (Cravit) 100mg , bid. before the one case 3 days after medication, after one case 7 days after medication were insomnia, excitement, could not sleep, and with continued symptoms of increased medication, 2 patients after treatment of insomnia symptoms disappear .2 excited patients were not taking other drugs during treatment, the authors believe that insomnia by the LVFX (Cravit) due.
4.3
Wang Dongyun Parkinson's disease [12] reported one case of male patients, aged 60, due to chronic bronchial inflammatory attack, taking LVFX (Beijing Erbitux new) 200mg, bid, with the amount of bromhexine regular service. after 2 days, dosage was reduced LVFX 100mg, bid. the first 3 days intractable hiccups, face expressionless, speech reduction and withdrawal. hiccups disappeared within 2 days after treatment, but have been slow to appear, writing difficulties, panic, unsteady gait and other symptoms, and gradually increase, resulting in standing firm, and fell 1. mental patients without neurological history, sane, no vomiting, normal vital signs, limb increased muscle tone, tendon reflexes, diminished or disappeared. The switch to a higher level Department of Neurology, a diagnosis of Parkinson's disease. The application of drugs such as trihexyphenidyl 1 week after treatment, the symptoms improved disappear. authors believe that the amount of patients with previous repeated conventional application of bromhexine no abnormal reaction, disable LVFX and anticholinergic drugs given shortly after the disappearance of the symptoms can be caused by Parkinson's disease that is LVFX.
4.4 Magic Cui Yu as
[13] reported one case of female patients, aged 76, under double-lung infection due to intravenous infusion of LVFX (to Ericsson) 0.1g, 2 times / d, see the disease in patients with medication the next day and shoot a lot of room ceiling mud flow, the infusion bottle is mud. conscious patients, the pathological negative for neurological consultation. medication 3 days after LVFX (to Ericsson) to ceftriaxone, and the remaining the same, dressing 3 days after the visual hallucinations disappeared.
4.5
Nan mental disorders [14] reported one case of female patients, aged 32, no spiritual past, neurological history, admitted to hospital because of incomplete intestinal obstruction, to decompression, intravenous injection LVFX, 2 days symptoms, 3 days ago suddenly visual hallucination auditory hallucination, visual inversion, image blur, unconscious laughing and crying, strip lying land. The investigation of liver and kidney function and electrolytes were normal, due to adverse reactions considered as LVFX. the withdrawal , 6h spirit returned to normal after the patient has no memory of history with .1 weeks after LVFX, patients and the above symptoms, immediately discontinued, relapse is not observed 4 days after discharge from hospital were followed up for six months, the spirit has always been normal.
5 adverse neuromuscular system neuromuscular syndrome
5.1
related Ming Wah [15] reported one case of female patients, aged 22, in the neck under general anesthesia, excision of lymphoma and 12 noon on the same day pm and 4 pm, two intravenous infusion of LVFX injection (Lee Fosun) 0.2g, 6 am the next day, the patient appeared stiff neck, limbs 3 times paroxysmal seizures, each lasting about 5min, followed by 30min interval and 20min, were conscious. consultation that the application of surgery droperidol (droperidol) induced extrapyramidal reaction after intramuscular injection of scopolamine given symptomatic relief to continue to give .11 Lee Fosun 0.2g, bid (twice the interval time of 1h), 2 pm, patients are again neck stiffness, limb convulsions 1, again resolved after intramuscular injection of scopolamine. Since then disable LVFX, no recurrence of similar symptoms, it can be identified adverse reactions due to LVFX. of that LVFX as quinolones, can cause central nervous system adverse reactions, and was positively correlated with the dose. 2 times the clinical dose of the short interval given continuously, dropping speed is also fast, caused by high blood concentration prone to cause adverse reactions. study confirmed that quinolones inhibit brain g-aminobutyric acid (GABA tyrosine) role, which led to a series of central nervous system symptoms, the degree of response was positively correlated with the dose, infusion time must not be less than 60min, twice infusion interval should be more than 1h.
5.2 rhabdomyolysis
Ho Mui [16] reported one case of male patients, 90 years old, upper respiratory tract infections due to oral administration of LVFX (Cravit) 0.1g, 3 times / d, next morning wake up feeling weak and fall, can not stand. pm admission, initially suspected: upper respiratory tract infection, drug allergy checks after the last confirmed by a variety of rhabdomyolysis with acute renal failure, consider LVFX cause. < br> 5.3 Achilles tendinitis
Sun Yongli [17] reported one case of male patients, aged 34, due to acute bronchitis intravenous infusion of LVFX (Sino-US joint venture in Suzhou of the Long March - Xinkai Pharmaceutical Co., Ltd.) 0.2g, bid, right foot pain medication 3 days later, did not dare touch the ground, orthopedic consultation: Achilles tendinitis. The disabled LVFX, bed rest, local heat, were discharged after 3 days. LVFX abroad have occurred related to reports of Achilles tendinitis. < br> 6 superinfection
Zhang Zheng [18] prospective study in 7 hospitals in Beijing to use all of LVFX injection drug users hospitalized patients .2661 cases of adverse reactions occurred in 105 cases of adverse reactions was 3.9% , where severe adverse reactions 4.8%, all double infection. LVFX irrational drug use accounted for 19.9%, focused on the elderly population over the age of 60, the main problem for the course too long or too short. unreasonable adverse drug reactions leading to direct cause of increased rates.
7 leukopenia
Wang Yan [19] reported one case of female patients, aged 32, hospital check WBC 4.4t109 / L, continuous epidural anesthesia in ovarian teratoma Excluding surgery, anti-inflammatory treatment 3 days after giving LVFX (to Ericsson) 0.2g, ivgtt, the first 4 days to give LVFX 0.2g, bid, review the WBC 2.8t109 / L, immediately stop LVFX, 3 days after the return to WBC 3.7 t109 / L, 10 days after the review return to WBC 9t109 / L, normal. The authors note that patients treated lactic LVFX anti-infective cause neutropenia, when the gradual recovery of white blood cells after treatment, indicating that the drug-related leukopenia and Clinical use of monitoring to the attention of LVFX blood, so as to avoid adverse consequences.
8
Li Wenhua hypoglycemic coma [20] reported 1 case of male patients, etc., 73 years old, 1 week due to diarrhea, fever 5 days, given LVFX 0.2g, ivgtt, bid and two octahedral smectite and other drugs, treatment for 6 days after diarrhea relief, for the consolidation effect, disable the other drugs, to continue to give LVFX, the first 10 days in patients with sudden confusion, check the trace peripheral blood glucose (FBG) 1.1mmoL / L, fasting blood glucose 0.77mmoL / L, a diagnosis of low blood sugar coma.
of: pete2188 Reply Date :2006-7-4 00:01:00
9 cardiovascular effects
9.1 QT interval prolongation
Samaha FF [21] reported one case of 88-year-old female patient after taking LVFX, QT interval prolongation 127ms, ventricular tachycardia occurred with atrial fibrillation. Therefore, the risk of serious cardiovascular disease, there is a history of arrhythmia, or electrolyte disorders in elderly patients with caution in patients with the drug. has been documented adverse reactions of quinolones, especially heart QT interval prolongation, so that the development of these drugs be restricted.
9.2 high blood pressure
LIU Ai [22] reported one case of male patients, 90 years old, because of bronchitis, pneumonia, lower right application of penicillin, cefazolin and other drug treatment is unknown, use LVFX (to Ericsson) intravenous (0.2g/100ml , qd), ampicillin / Shuba Tanner, cloth pseudo-ephedrine tablets, when the first group 1 LVFX 40min infusion, the patients with chills, shivering, chest, hands and feet get cold, T 37.9 ��, BP 253/14.7kPa ( 190/110mmHg), the disabled LVFX, given nifedipine, dexamethasone and other drugs, and to the physical cooling, 20min after the blood pressure dropped to BP 18.7/12.0kPa (140/90mmHg), continue to use ampicillin / Shuba Tanzania sodium drug treatment, no adverse reactions.
10 autoimmune hemolytic anemia
U.S. OH [23] reported 1 case of men such as white patients, 82 years old, due to the use of LVFX 10d cellulitis (500mg / d). after the result of severe jaundice, dizziness, fatigue, shortness of breath, dark urine and loss of vision to the emergency room, diagnosed with levofloxacin caused by autoimmune hemolytic anemia, received prednisone and the input concentration RBC PRBCs cured. The author believes that levofloxacin Although hemolytic anemia caused by an extremely rare but potentially lethal, should be immediately discontinued, and treatment for hemolytic anemia. for the use of fluoroquinolones hemolytic anemia patients, disabled levofloxacin.
11 other
LVFX as one of the national essential drugs are widely used in clinic. but because of the existence of these adverse reactions, use should pay attention to: (1) strictly dose regimen. LVFX at dose of 300 ~ 400mg, up to 600mg, more than the dose increased the incidence of side effects; high-dose or long-term applications are prone to cause liver damage [25,26]. it should pay attention to the clinical application of drug dose and treatment, try not to overdose medication, treatment should not be too long, especially for the elderly and the liver in patients with renal insufficiency the dosage should be strictly controlled and the treatment, when necessary, blood concentration monitoring, individualized drug administration. (2) seriously asked allergy history. LVFX side effects in patients with no history of allergy incidence 2.75%, a history of allergy was 4.47%, with significant differences (P <0.05) [24]. This product is not used for any kind of quinoline Well ketone who are allergic to antibiotics, because these drugs cross-reactivity between species [25,26]. Clinical whether patients should be asked in detail about the history of drug and food allergy, there is the history of penicillin allergy and allergic caution. (3) LVFX and combined with other drugs drug interactions may occur, therefore, permit conditions, concomitant medications should be minimized. (4) the elderly may be complicated by a variety of organs as disease, liver and kidney function decreased, compared prone to side effects, especially LVFX mainly from the kidney metabolism, reduction of required clinical treatment, if necessary, monitoring of renal function. In order to ensure drug safety, children should be disabled LVFX, 18 young people under the age of caution is appropriate, In addition, the clinical application require special attention to women, pregnant women, breastfeeding women should be banned [25,26]. (5) adverse reaction should be immediately discontinued, symptomatic treatment promptly.
of: pete2188 Reply Date :2006-7-4 00:03:00
��Reference��
1 Lvli Bo, Zhang Jing. levofloxacin in the treatment of tuberculosis caused by side effects clinical observation and treatment of 24 cases. Qiqihar Medical College, 2002,23 (3): 271.
2 Wu Xia. ascites caused by levofloxacin. Adverse Drug Reactions Journal, 2004,6 (6): 407.
3 Wu Wei Yan, Xie Ping. levofloxacin caused by severe allergic drug eruption. Journal of Adverse Drug Reactions, 1999, 1 (3): 186.
4 Long Gui-Ying, ZHU Wei-hua. anaphylactic shock caused by levofloxacin. Adverse Drug Reactions Journal, 2002,4 (2): 131.
5 Yangming Na, Sun Qing, Dong Feng. levofloxacin Anaphylactic shock caused by elderly patients in 2 cases. journal Adverse Drug Reactions, 2003,5 (1): 56.
6 Zhuang Shuping, Xingyue Ping, Xing Luying. Levofloxacin injection induced delayed allergic reaction in 5 cases. Medicine, 2002 , 21 (9) :581-581.
7 Liang Pi-xia, Yang Zhao Xu. Ashland Levofloxacin induced a Hengnuo syndrome in 1. Journal of Internal Medicine, 2000,39 (3): 209.
8 ��extension, the Sun Jian, Zhang Guangfang. Levofloxacin 1 case of anaphylaxis. Chinese Journal of New Drugs, 2002,11 (3) :253-253.
9 Yin Lihua. Levofloxacin Lactate Injection 1 case caused by hand-foot skin scaling. Chinese Journal of Clinical Pharmacy 2001,10 (4) :261-261.
10 beam winter months. levofloxacin caused by facial muscle twitch. Adverse Drug Reactions Journal, 2000,2 (4): 266.
11 Chen Zelian, management governance, Pan Xiaoou. levofloxacin cause insomnia in 2 cases, West China Medical Journal, 2003,18 (3): 402.
12 Wang Dongyun. oral levofloxacin induced Parkinson's syndrome in 1. Chinese Journal of Clinical Medicine, 2003,22 (7 ) :443-444.
13 Cui Yu, Lan Jian Hong. Intravenous mental abnormalities in 2 patients. Chinese Journal of New Drugs, 2003,12 (6) :428-428.
15 Guan Ming Hua, Song. levofloxacin caused by neck stiffness, limb convulsions. Adverse Drug Reactions Journal, 2001,3 ( 2): 125.
16 Ho Mui, places Yin Kong. rhabdomyolysis caused by levofloxacin case. Journal of Internal Medicine, 2001,40 (12): 880.
17 Sun Yongli, Zhao Jinrong. 1 Achilles tendinitis caused by levofloxacin cases. Clinical, 2004,32 (2): 44.
18 Zhang Zheng, Yan Jian-Cun, Zhan Siyan. Levofloxacin injection drug adverse reactions and forward-looking rational observation. Chinese Journal of Epidemiology, 2001,22 (6) :405-407.
19 Wang Yan, Chen Su husband, Xiong Xiaoyan, et al. Levofloxacin Lactate induced leukopenia. Adverse Drug Reactions Journal, 2002,4 (2): 125.
20 Li Wenhua, Li Jian, Wang Nan. Levofloxacin Mesylate 1 case of coma caused by low blood sugar. Chinese Journal of Clinical Pharmacy, 2002,11 (1): 40.
21 Samaha FF.QTC interval prolongation and polymorphic ventricular tachycardia in association with levofloxacin.Am J Med, 1999,107 (5) :528-529.
22 LIU Ai, Jian Liu. to Ericsson to serious hypertension in 1. Modern Applied Pharmacy, 2003,20 (6): 529.
23 Oh YR, Carr-Lopezi SM, Probasco JM, et al.Levofloxacin-induced autoimmune hemolytic anemia.Ann Pharmacother ,2003,37:1010-1013.
24 Liang Yan, Lu Yunlan. levofloxacin and adverse reactions relevant factors. China Medical Tribune ,2002-07-18.
25 National Pharmacopoeia Committee. Clinical Guide to the Chinese Pharmacopoeia (2000 edition). Beijing: Chemical Industry Press ,2001,702-707.
26 Chen Xinqian, gold has Yu, Tang light. New Pharmacy, 15th edition. Beijing: People Health Press ,2003,104-106.
Author: 655000 Yunnan Qujing, the First People's Hospital Pharmacy Qujing
(Editor: Tian)
news
cause seizures intravenous levofloxacin levofloxacin mesylate 2 cases of respiratory infection
needle levofloxacin analysis of 135 cases of adverse side effects caused by levofloxacin 78 cases
2, the doctor said then save a minute later, my throat will be completely closed, must directly cut, intubation breathing. There is also a land approach to the animals injected with about dozens of the huge number of needle directly to the neck and tie a big hole. breathes breathing.
3, the speech difficulties, I get the usual low-key deep nonsense, just with open tears bark, and the innocent and helpless, pathetic, sort of a small two eyes, separated glasses, nostalgia, looking at the world. think of the money not spent finished, people do not love enough, the sadness of parting, with mixed feelings. < br> 4, hula family came to the hospital. Our family Daniu rushing tears. Erniu indifferent to our house (since she can never expect to eat great dragon (Wing) shrimp).
5, yesterday afternoon and evening, to drink cup of warm boiled water reached nearly to eat watermelon two, the mouth piece with a dozen VC buccal tablets. crazy sweating, urinating on the toilet an average of five minutes once. finally left grams (levofloxacin injection) is scheduled to be almost the same.
6, now no longer face pale, Yin-Tang no longer blue, his voice has been able to speak. Daniu said: Silent cute, now you're restored to the world's most annoying bitch. is certainly not an injection. can not resolve injection infusion.
2, not because hospitals everywhere when you are president of the iron sister, Director of Nursing you have no big problems go to the hospital to play. accounting for the mental hospital cheap no longer there. more not to lie and they want to talk to his girlfriend on an intravenous drip.
3, left millions of caution grams (Levofloxacin Hydrochloride Injection) and all easy to allergy medications. my daughter was allergic to penicillin are also shock . if you feel unwell, do not hesitate, do not observe an immediate pull fluid.
4, said her daughter went to the hospital to see me cry I think the way: my mom giant strong man, and never trouble people. certainly only for his family to die, son wants his parents away, but Mom did not know women want to study. So little friends to remind you learn every day, do not let my parents worry.
Here is what I left in the online search grams of allergy cases reflect:
of : pete2188 filing date :2006-7-3 23:53:37
girlfriend a few days ago with fever fever of 39 degrees, go to Shanghai Punan hospital emergency room doctor on duty for a blood test, then decided to give fluids, we remind penicillin allergy The doctor said that he cephalosporins? We asked cephalosporins penicillin allergy can play it? decided to play left-grams, 0.3g (5% glucose 500ml) * 3 days, things started from the left-grams. infusion also reclaim heat for two days, during accompanied by dizziness, palpitation, suffocation, cold sweat, excitement, headache, insomnia, nausea, skin rash (purpura, systemic showed migratory pain), consult a doctor, saying that there is a cooling process. to continue treatment. end of the day infusion, heat has not yet retired, also increased the diarrhea, the body was becoming more and more migratory severe pain, allergic purpura red dot increases. can be said that all the side effects of left grams have emerged. I really do not know the manufacturer and the hospital how the services for patients.
We hope that we note that levofloxacin with hydrochloric acid when the alert to avoid the physical suffering of more pain ..
: pete2188 Reply Date :2006 -7-323: 54:00
Here is another User's Friendly reminder: the left g (Levofloxacin Hydrochloride Injection)
Indications:
This product applies to the following sensitive bacteria in severe infections: 1. Respiratory infections: acute bronchitis, acute exacerbation of chronic bronchitis, diffuse bronchitis, bronchiectasis with infection, pneumonia, tonsillitis (peritonsillar abscess). 2. Urinary tract infections: pyelonephritis, complicated urinary tract infections 3.. reproductive system infections: acute prostatitis, acute inflammation epididymis, uterine infection, uterine annex inflammation, pelvic inflammatory disease (suspected anaerobic infections can be combined with metronidazole). 4. skin and soft tissue infections: infectious pus blister disease, cellulitis, lymphatic (node) inflammation, subcutaneous abscess, anal abscess. 5. gastro-intestinal infections: bacillary dysentery, infectious enteritis, salmonella enteritis, typhoid and paratyphoid. 6. sepsis, granulocyte cells decreased and immunocompromised patients with various infections. 7. Other infections: mastitis, trauma, burns and surgical wound infection, abdominal infection (combined with metronidazole if necessary), cholecystitis, cholangitis, bone and joint infections and ENT infections.
��Usage and Dosage��:
intravenous drip: Adult daily 0.4g, 2 times intravenous infusion. pathogen of severe infection and is less sensitive to the chemicals (such as Pseudomonas aeruginosa Aeromonas), maximum daily dose can be increased to 0.6g, intravenous infusion of 2 times.
grams for the left, to note that its side effects. Of course, all the drugs will have side effects.
from the north Medical Hospitals Allergy symptoms will not occur. However, to avoid the occurrence of allergic symptoms, requirements: the infusion time, the slow trickle. usual dose vials, the input of not less than one hours time.
this knowledge because of the recent their loved ones, lost in half an hour left over .24 grams or more hours there than that, in addition to all the allergy symptoms of vertigo: First, rapid heart rate, chest tightness, shortness of breath, nausea, headache, high fever does not retreat excited can not sleep, then whole body and face skin rash and erythema, it is painful
of: pete2188 Reply Date :2006-7-3 23:57:00
Chief Medical Network>> Magazine>> China Modern Clinical Medicine> net Zhou Hui 2006-2-23 21:39:03 Journal of Modern Clinical Medicine January 2006 Volume 4 No. 2
Keywords: Levofloxacin
Abstract In this paper, recent years on levofloxacin (LVFX) documentation of adverse reactions to summarize, the main side effects include gastrointestinal reactions, allergic reactions, and central nervous system reactions. prompted the clinical use of the drug when in the stricter control over their indications, take the right to use, and careful combination to avoid and reduce adverse reactions.
Key words levofloxacin; adverse reactions
levofloxacin (levofloxacin, LVFX) was first developed in 1994 by the Japanese successfully developed, it is the 3rd generation quinolone antibacterial drug is the racemic ofloxacin enantiomer, the antibacterial spectrum covering gram-positive bacteria, Gram-negative bacteria, anaerobic bacteria, atypical pathogens, and mycobacteria. In vitro antibacterial activity of oxygen 2 times the fluoride Sand Star, D-Body (R-OFLX), 8 ~ 128 times. oral bioavailability, tissue permeability, can be quickly distributed to various organizations, long half-life, 85% through urine excretion. extensive for respiratory, gastroenterology, gynecology, dermatology, surgery and other departments. In this paper, the past 5 years at home and abroad about the adverse effects of levofloxacin appears to summarize the literature data, are summarized below.
1 gastrointestinal reaction
Lv Libo [1] and reported in the treatment of tuberculosis with LVFX injection in 24 patients with varying degrees of side effects: gastrointestinal reactions including 10 cases (41.67%), dizziness, headache in 6 patients (25.00%), pruritus, rash in 5 patients (20.83%), fever, heart palpitations in 2 cases (8.33%), blood urea nitrogen increased 1 (4.17%). All of the above adverse symptoms disappeared after stopping.
2 induced ascites
Wu Xia [2] reported 1 patient was male, 23 years old, a university student. because of headache, sore throat, fever 2 days, on the evening of 21 June 2003 10:00 to treatment. Patients usually physical health, no history of drug allergy . doctors, giving LVFX 200 mg intravenous infusion of 1. 5:00 am the next day, patients with nausea, abdominal distension, abdominal pain, diarrhea, abdominal palpation can be heard, and shifting dullness. B ultrasound diagnosis: ascites (in volume). Disable LVFX. immediate 5% glucose injection 500ml + intravenous dexamethasone 15mg, furosemide 20mg intramuscular injection, intravenous infusion of 20% mannitol 250ml. 8:00 am on day 2, patients with these symptoms, review B- showed no abnormal echo abdominal .2004 Jan. 2, the patient re-infusion LVFX 200mg, once again the above symptoms, B ultrasound diagnosis of ascites. by using the same measures after treatment and gradually returned to normal after the drug is not used, then did not have the symptoms, so consider patients with ascites due to LVFX.
3 allergic reaction allergic drug eruption
3.1 Wu Wei Yan [3] reported one case of female patients suffering from acute purulent tonsillitis intravenous levofloxacin mesylate (Lee Fosun), skin rash during the infusion, the patient in the event of no notice after drug eruption, outdoor activities are more sun, skin rash was worse. of the opinion that the product has a phototoxic reaction (occurring rate of <1%), may result in increased symptoms.
3.2 anaphylactic shock
1 patients with 23-year-old female patient [4], the FDA due to acute gastroenteritis 100ml, dropping speed of 30 drops / min. medicine 5min after the dizziness, limb numbness, followed by symptoms of anaphylactic shock. quickly to anti-shock treatment, about 15min after the above symptoms gradually improved, blood pressure, pulse, respiration returned to normal consciousness turned clear.
3.3 speed hair and delayed type hypersensitivity
Yangming Na [5] reported LVFX induced anaphylactic shock in elderly patients in 2 cases, 1 male patients, aged 82, the patient again in 2 days intravenous infusion of hydrochloric acid LVFX 2min only about the first appears dizziness, sweating, fatigue, hold breath, accompanied by a transient disturbance of consciousness.
LVFX not only led to immediate hypersensitivity, has also led to delayed allergic reactions. Zhuangshu Ping [6] reported that in February 2001, in the sections of their total of 98 patients using the injection LVFX HCl, 5 patients had symptoms of delayed allergic reactions, usually 8 to 12 days treatment appears to have been discontinued and allergy treatment improved. were denied the application in the treatment of other cause during allergy medicine and food, so consider delayed allergic reactions caused by LVFX Department of hydrochloric acid.
3.4 Ashland - Hengnuo syndrome
Liang Pi-xia [7] reported 1 case of female patients, 62 years old, no history of drug allergy, for and excellent surge levels. The next morning there were large migratory joint swelling and pain the whole body, with skin congestion, limited mobility. from the elbow to the knee, wrist, ankle involvement in turn, first right after the left side. At the same time Ministry of right elbow, left knee, right leg and bilateral hip extensor surface of bleeding papules, sizes and irregular, non-itching. with paroxysmal abdominal pain, nausea and vomiting. to the hospital to joint pain of unknown origin, The above symptoms improved, were discharged after 10 days.
3.5 limbs, face, abdomen numbness
m extension from [8] reported 1 case of female patients, aged 28, due to intravenous infusion of upper respiratory tract infection Bupleurum injection, LVFX HCl injection (left grams), medication suddenly felt numbness in patients after 30min, and then the face, abdomen numb, his hands itching, difficult to tolerate, no rash appears. the withdrawal, to give 10% calcium gluconate injection solution, 5% glucose injection, itching stopped after about 10min, then the limbs, face, abdomen numbness have disappeared. The next day, still with the Bupleurum injection fever, and the other using tobramycin injection (properly Xin), until the patients recovered without any adverse reactions occur again. so that the occurrence of allergic reactions are caused by the hydrochloric acid injection LVFX.
of: pete2188 Reply Date :2006-7-4
3.6 off hand-foot skin Chip
Yin Lihua [9] reported 1 case of female patients, aged 70, due to secondary infection of bronchial asthma given aminophylline and LVFX (to Ericsson) 100mg, ivgtt, bid.3 days after the hand-foot skin itching, scaling, that disabled LVFX, 1 week after symptoms of hand-foot skin scaling improved again after 3 months in patients with application of LVFX and aminophylline, 1 day and hand-foot skin itching, scaling, disable LVFX 1 month later, the skin off Chip symptoms.
4 central nervous system reactions, and mental disorders
4.1
epilepsy beam winter months [10] reported one case of female patients, aged 17, in gonadal resection of epidural anesthesia for the prevention of infection, intravenous infusion of LVFX injection 0.4g / d. Enter 100ml 2 days later, the patient suddenly felt the whole body discomfort, facial muscle tension, twitching, eyes forced upward gaze, not closed, sweat more. But the mind clear, accurate answer , denied a history of epilepsy, and other related. examination: P 134 times / min, R 20 times / min, BP 18.0/12.0kPa (135/90mmHg). that disabled LVFX to diazepam (stable), were quiet after treatment sleep, the symptoms disappeared again after .2 h whole body discomfort, mild opisthotonus, again to the stability of symptoms and stable condition. after the switch to penicillin, no recurrence of similar reactions. authors suggest that LVFX inhibits g-aminobutyric acid Therefore, to induce epilepsy. The sudden appearance of patients in the infusion of muscle tension, twitching, eyes forced upward gaze, sweat more, may be caused by epilepsy LVFX. a history of epilepsy should be careful using this, without a history of epilepsy also should be noted.
4.2
Chen Zelian insomnia [11] reported 2 cases of female patients: 1 case of 39-year-old, the other 1 case of 32-year-old, respectively, because of cough, urinary tract infection oral LVFX (Cravit) 100mg , bid. before the one case 3 days after medication, after one case 7 days after medication were insomnia, excitement, could not sleep, and with continued symptoms of increased medication, 2 patients after treatment of insomnia symptoms disappear .2 excited patients were not taking other drugs during treatment, the authors believe that insomnia by the LVFX (Cravit) due.
4.3
Wang Dongyun Parkinson's disease [12] reported one case of male patients, aged 60, due to chronic bronchial inflammatory attack, taking LVFX (Beijing Erbitux new) 200mg, bid, with the amount of bromhexine regular service. after 2 days, dosage was reduced LVFX 100mg, bid. the first 3 days intractable hiccups, face expressionless, speech reduction and withdrawal. hiccups disappeared within 2 days after treatment, but have been slow to appear, writing difficulties, panic, unsteady gait and other symptoms, and gradually increase, resulting in standing firm, and fell 1. mental patients without neurological history, sane, no vomiting, normal vital signs, limb increased muscle tone, tendon reflexes, diminished or disappeared. The switch to a higher level Department of Neurology, a diagnosis of Parkinson's disease. The application of drugs such as trihexyphenidyl 1 week after treatment, the symptoms improved disappear. authors believe that the amount of patients with previous repeated conventional application of bromhexine no abnormal reaction, disable LVFX and anticholinergic drugs given shortly after the disappearance of the symptoms can be caused by Parkinson's disease that is LVFX.
4.4 Magic Cui Yu as
[13] reported one case of female patients, aged 76, under double-lung infection due to intravenous infusion of LVFX (to Ericsson) 0.1g, 2 times / d, see the disease in patients with medication the next day and shoot a lot of room ceiling mud flow, the infusion bottle is mud. conscious patients, the pathological negative for neurological consultation. medication 3 days after LVFX (to Ericsson) to ceftriaxone, and the remaining the same, dressing 3 days after the visual hallucinations disappeared.
4.5
Nan mental disorders [14] reported one case of female patients, aged 32, no spiritual past, neurological history, admitted to hospital because of incomplete intestinal obstruction, to decompression, intravenous injection LVFX, 2 days symptoms, 3 days ago suddenly visual hallucination auditory hallucination, visual inversion, image blur, unconscious laughing and crying, strip lying land. The investigation of liver and kidney function and electrolytes were normal, due to adverse reactions considered as LVFX. the withdrawal , 6h spirit returned to normal after the patient has no memory of history with .1 weeks after LVFX, patients and the above symptoms, immediately discontinued, relapse is not observed 4 days after discharge from hospital were followed up for six months, the spirit has always been normal.
5 adverse neuromuscular system neuromuscular syndrome
5.1
related Ming Wah [15] reported one case of female patients, aged 22, in the neck under general anesthesia, excision of lymphoma and 12 noon on the same day pm and 4 pm, two intravenous infusion of LVFX injection (Lee Fosun) 0.2g, 6 am the next day, the patient appeared stiff neck, limbs 3 times paroxysmal seizures, each lasting about 5min, followed by 30min interval and 20min, were conscious. consultation that the application of surgery droperidol (droperidol) induced extrapyramidal reaction after intramuscular injection of scopolamine given symptomatic relief to continue to give .11 Lee Fosun 0.2g, bid (twice the interval time of 1h), 2 pm, patients are again neck stiffness, limb convulsions 1, again resolved after intramuscular injection of scopolamine. Since then disable LVFX, no recurrence of similar symptoms, it can be identified adverse reactions due to LVFX. of that LVFX as quinolones, can cause central nervous system adverse reactions, and was positively correlated with the dose. 2 times the clinical dose of the short interval given continuously, dropping speed is also fast, caused by high blood concentration prone to cause adverse reactions. study confirmed that quinolones inhibit brain g-aminobutyric acid (GABA tyrosine) role, which led to a series of central nervous system symptoms, the degree of response was positively correlated with the dose, infusion time must not be less than 60min, twice infusion interval should be more than 1h.
5.2 rhabdomyolysis
Ho Mui [16] reported one case of male patients, 90 years old, upper respiratory tract infections due to oral administration of LVFX (Cravit) 0.1g, 3 times / d, next morning wake up feeling weak and fall, can not stand. pm admission, initially suspected: upper respiratory tract infection, drug allergy checks after the last confirmed by a variety of rhabdomyolysis with acute renal failure, consider LVFX cause. < br> 5.3 Achilles tendinitis
Sun Yongli [17] reported one case of male patients, aged 34, due to acute bronchitis intravenous infusion of LVFX (Sino-US joint venture in Suzhou of the Long March - Xinkai Pharmaceutical Co., Ltd.) 0.2g, bid, right foot pain medication 3 days later, did not dare touch the ground, orthopedic consultation: Achilles tendinitis. The disabled LVFX, bed rest, local heat, were discharged after 3 days. LVFX abroad have occurred related to reports of Achilles tendinitis. < br> 6 superinfection
Zhang Zheng [18] prospective study in 7 hospitals in Beijing to use all of LVFX injection drug users hospitalized patients .2661 cases of adverse reactions occurred in 105 cases of adverse reactions was 3.9% , where severe adverse reactions 4.8%, all double infection. LVFX irrational drug use accounted for 19.9%, focused on the elderly population over the age of 60, the main problem for the course too long or too short. unreasonable adverse drug reactions leading to direct cause of increased rates.
7 leukopenia
Wang Yan [19] reported one case of female patients, aged 32, hospital check WBC 4.4t109 / L, continuous epidural anesthesia in ovarian teratoma Excluding surgery, anti-inflammatory treatment 3 days after giving LVFX (to Ericsson) 0.2g, ivgtt, the first 4 days to give LVFX 0.2g, bid, review the WBC 2.8t109 / L, immediately stop LVFX, 3 days after the return to WBC 3.7 t109 / L, 10 days after the review return to WBC 9t109 / L, normal. The authors note that patients treated lactic LVFX anti-infective cause neutropenia, when the gradual recovery of white blood cells after treatment, indicating that the drug-related leukopenia and Clinical use of monitoring to the attention of LVFX blood, so as to avoid adverse consequences.
8
Li Wenhua hypoglycemic coma [20] reported 1 case of male patients, etc., 73 years old, 1 week due to diarrhea, fever 5 days, given LVFX 0.2g, ivgtt, bid and two octahedral smectite and other drugs, treatment for 6 days after diarrhea relief, for the consolidation effect, disable the other drugs, to continue to give LVFX, the first 10 days in patients with sudden confusion, check the trace peripheral blood glucose (FBG) 1.1mmoL / L, fasting blood glucose 0.77mmoL / L, a diagnosis of low blood sugar coma.
of: pete2188 Reply Date :2006-7-4 00:01:00
9 cardiovascular effects
9.1 QT interval prolongation
Samaha FF [21] reported one case of 88-year-old female patient after taking LVFX, QT interval prolongation 127ms, ventricular tachycardia occurred with atrial fibrillation. Therefore, the risk of serious cardiovascular disease, there is a history of arrhythmia, or electrolyte disorders in elderly patients with caution in patients with the drug. has been documented adverse reactions of quinolones, especially heart QT interval prolongation, so that the development of these drugs be restricted.
9.2 high blood pressure
LIU Ai [22] reported one case of male patients, 90 years old, because of bronchitis, pneumonia, lower right application of penicillin, cefazolin and other drug treatment is unknown, use LVFX (to Ericsson) intravenous (0.2g/100ml , qd), ampicillin / Shuba Tanner, cloth pseudo-ephedrine tablets, when the first group 1 LVFX 40min infusion, the patients with chills, shivering, chest, hands and feet get cold, T 37.9 ��, BP 253/14.7kPa ( 190/110mmHg), the disabled LVFX, given nifedipine, dexamethasone and other drugs, and to the physical cooling, 20min after the blood pressure dropped to BP 18.7/12.0kPa (140/90mmHg), continue to use ampicillin / Shuba Tanzania sodium drug treatment, no adverse reactions.
10 autoimmune hemolytic anemia
U.S. OH [23] reported 1 case of men such as white patients, 82 years old, due to the use of LVFX 10d cellulitis (500mg / d). after the result of severe jaundice, dizziness, fatigue, shortness of breath, dark urine and loss of vision to the emergency room, diagnosed with levofloxacin caused by autoimmune hemolytic anemia, received prednisone and the input concentration RBC PRBCs cured. The author believes that levofloxacin Although hemolytic anemia caused by an extremely rare but potentially lethal, should be immediately discontinued, and treatment for hemolytic anemia. for the use of fluoroquinolones hemolytic anemia patients, disabled levofloxacin.
11 other
LVFX as one of the national essential drugs are widely used in clinic. but because of the existence of these adverse reactions, use should pay attention to: (1) strictly dose regimen. LVFX at dose of 300 ~ 400mg, up to 600mg, more than the dose increased the incidence of side effects; high-dose or long-term applications are prone to cause liver damage [25,26]. it should pay attention to the clinical application of drug dose and treatment, try not to overdose medication, treatment should not be too long, especially for the elderly and the liver in patients with renal insufficiency the dosage should be strictly controlled and the treatment, when necessary, blood concentration monitoring, individualized drug administration. (2) seriously asked allergy history. LVFX side effects in patients with no history of allergy incidence 2.75%, a history of allergy was 4.47%, with significant differences (P <0.05) [24]. This product is not used for any kind of quinoline Well ketone who are allergic to antibiotics, because these drugs cross-reactivity between species [25,26]. Clinical whether patients should be asked in detail about the history of drug and food allergy, there is the history of penicillin allergy and allergic caution. (3) LVFX and combined with other drugs drug interactions may occur, therefore, permit conditions, concomitant medications should be minimized. (4) the elderly may be complicated by a variety of organs as disease, liver and kidney function decreased, compared prone to side effects, especially LVFX mainly from the kidney metabolism, reduction of required clinical treatment, if necessary, monitoring of renal function. In order to ensure drug safety, children should be disabled LVFX, 18 young people under the age of caution is appropriate, In addition, the clinical application require special attention to women, pregnant women, breastfeeding women should be banned [25,26]. (5) adverse reaction should be immediately discontinued, symptomatic treatment promptly.
of: pete2188 Reply Date :2006-7-4 00:03:00
��Reference��
1 Lvli Bo, Zhang Jing. levofloxacin in the treatment of tuberculosis caused by side effects clinical observation and treatment of 24 cases. Qiqihar Medical College, 2002,23 (3): 271.
2 Wu Xia. ascites caused by levofloxacin. Adverse Drug Reactions Journal, 2004,6 (6): 407.
3 Wu Wei Yan, Xie Ping. levofloxacin caused by severe allergic drug eruption. Journal of Adverse Drug Reactions, 1999, 1 (3): 186.
4 Long Gui-Ying, ZHU Wei-hua. anaphylactic shock caused by levofloxacin. Adverse Drug Reactions Journal, 2002,4 (2): 131.
5 Yangming Na, Sun Qing, Dong Feng. levofloxacin Anaphylactic shock caused by elderly patients in 2 cases. journal Adverse Drug Reactions, 2003,5 (1): 56.
6 Zhuang Shuping, Xingyue Ping, Xing Luying. Levofloxacin injection induced delayed allergic reaction in 5 cases. Medicine, 2002 , 21 (9) :581-581.
7 Liang Pi-xia, Yang Zhao Xu. Ashland Levofloxacin induced a Hengnuo syndrome in 1. Journal of Internal Medicine, 2000,39 (3): 209.
8 ��extension, the Sun Jian, Zhang Guangfang. Levofloxacin 1 case of anaphylaxis. Chinese Journal of New Drugs, 2002,11 (3) :253-253.
9 Yin Lihua. Levofloxacin Lactate Injection 1 case caused by hand-foot skin scaling. Chinese Journal of Clinical Pharmacy 2001,10 (4) :261-261.
10 beam winter months. levofloxacin caused by facial muscle twitch. Adverse Drug Reactions Journal, 2000,2 (4): 266.
11 Chen Zelian, management governance, Pan Xiaoou. levofloxacin cause insomnia in 2 cases, West China Medical Journal, 2003,18 (3): 402.
12 Wang Dongyun. oral levofloxacin induced Parkinson's syndrome in 1. Chinese Journal of Clinical Medicine, 2003,22 (7 ) :443-444.
13 Cui Yu, Lan Jian Hong. Intravenous mental abnormalities in 2 patients. Chinese Journal of New Drugs, 2003,12 (6) :428-428.
15 Guan Ming Hua, Song. levofloxacin caused by neck stiffness, limb convulsions. Adverse Drug Reactions Journal, 2001,3 ( 2): 125.
16 Ho Mui, places Yin Kong. rhabdomyolysis caused by levofloxacin case. Journal of Internal Medicine, 2001,40 (12): 880.
17 Sun Yongli, Zhao Jinrong. 1 Achilles tendinitis caused by levofloxacin cases. Clinical, 2004,32 (2): 44.
18 Zhang Zheng, Yan Jian-Cun, Zhan Siyan. Levofloxacin injection drug adverse reactions and forward-looking rational observation. Chinese Journal of Epidemiology, 2001,22 (6) :405-407.
19 Wang Yan, Chen Su husband, Xiong Xiaoyan, et al. Levofloxacin Lactate induced leukopenia. Adverse Drug Reactions Journal, 2002,4 (2): 125.
20 Li Wenhua, Li Jian, Wang Nan. Levofloxacin Mesylate 1 case of coma caused by low blood sugar. Chinese Journal of Clinical Pharmacy, 2002,11 (1): 40.
21 Samaha FF.QTC interval prolongation and polymorphic ventricular tachycardia in association with levofloxacin.Am J Med, 1999,107 (5) :528-529.
22 LIU Ai, Jian Liu. to Ericsson to serious hypertension in 1. Modern Applied Pharmacy, 2003,20 (6): 529.
23 Oh YR, Carr-Lopezi SM, Probasco JM, et al.Levofloxacin-induced autoimmune hemolytic anemia.Ann Pharmacother ,2003,37:1010-1013.
24 Liang Yan, Lu Yunlan. levofloxacin and adverse reactions relevant factors. China Medical Tribune ,2002-07-18.
25 National Pharmacopoeia Committee. Clinical Guide to the Chinese Pharmacopoeia (2000 edition). Beijing: Chemical Industry Press ,2001,702-707.
26 Chen Xinqian, gold has Yu, Tang light. New Pharmacy, 15th edition. Beijing: People Health Press ,2003,104-106.
Author: 655000 Yunnan Qujing, the First People's Hospital Pharmacy Qujing
(Editor: Tian)
news
cause seizures intravenous levofloxacin levofloxacin mesylate 2 cases of respiratory infection
needle levofloxacin analysis of 135 cases of adverse side effects caused by levofloxacin 78 cases
Sunday, February 20, 2011
Fate of the car in 2007 and thinking
Fate of the car in 2007 and thinking
Gu Qingsheng
2007 spring one from the south to Beijing, I went to find a common drink PR, I thought it was a Banquet, it, too. Why GM public relations I find it? An Xiang mainly because I wrote a piece on the car, in Back in 2007, when I played this piece in particular memory. as follows:
in China within a large valley, a detour to a new car parts, sun shining, shimmering metallic sheen. It does not know who the owner, I do not know ancient or modern, I do not know is the earth, or aliens, in short, I do not know to place. One day, Germany people playing here before, peruse, pick out the demolition of refined automotive wrench away, about his lack of such a wrench kit. Then came one of the Japanese, the Japanese took out pen and paper, the zero Parts painted it again, take nothing, go back to the repairer according to the drawings. after the arrival of the Chinese people as the Japanese, quickly took out the camera while Kuangpai, and then get the magazine to express: I national archaeological discoveries have , Prehistoric Men will repairer, and there are auto parts to prove it. the Americans finally came and looked at, the estimated model can be fitted into a good car, begins with the foot shouting come and spend money that they would spare parts loaded into a car, a Buick trademark black of the paste, it becomes a Buick or Chevrolet car, place to sell a good price.
I stop writing this piece, and my heart has always been very satisfied General public relations may not think of this dissatisfaction, there is no poetry in an era, people like to read fables, at best, only said that Americans are business-minded than other people, GM is also so fragile? drink to half of the general public relations go, I left one child to drink slowly. He said he was busy, I is not busy, I was working on the school, Lin Hui from the Zhongguancun Tongzhou drink a month for Han Hao.
words on to the Shanghai auto show, I also spent half a hurry will go to Chongqing Book Fair. after four months did not care about cars, virgin forests and Tibetan Plateau not the Internet. Simply put, I like the car in 2007 from farther away. Fortunately, back to Beijing, found the Chinese auto elite group, the QQ chat group every day cars, I have been told I look for wheat to a 212, the process to such a more.
addition, Anhai found the car features three cities, Chengdu is a city car the most complex, from the Alto to the Audi, what series of cars slowly walking in the streets. Gein Chengdu, free and easy consumer concept, to consume what car to buy cars, and will not tiptoe to buy luxury cars filling wide, I think that is the wisdom of the people of Chengdu. But to go to Shenyang, I often go to a decade ago, when the streets to do in Shenyang running head soil soil refuse of the brain, and now many of the streets ran dry frog simmer Hash General Audi. Yangzhou other information is received, the city's private cars accounted for 40%, which is the largest city with private cars . because in Yangzhou, a private car can also be put into operation, is a tourist city of Yangzhou, 24, no bridge, then swam around the Slender West Lake.
words to say to the front of the piece, in fact, Asian countries it is the general mentality of people . After all general dissatisfaction, it may care about OEM, but OEM Anjiu see GM Wuling, ditch in the mountains, there are many, it does hold up a common sales performance. In addition, I at least In the four provinces take the general business class. I feel that GM might sell a good business position, as well as GM-Wuling sold well, a bit Daya and vulgar taste. this comparison, I also towards national brands shift in this direction, while mid-range sprint cars, while maintaining the manufacturing economy.
I ordered the country is developing its own brand in the state, the first half of the automobile market through the stock market sun shone nice and warm, in the second half with the stock market's ups and downs, the automobile market there panic-type sell-off, the storm has arrived. In this period, particularly oil rising to 10% of the benchmark, the general impact of such enterprises will certainly be. And the slowdown in the market its own brand, I that the benefit of its own brand, be it 10 minutes out of a car assembly line, you can put out one to 20 minutes, and that work will seem fine than before.
overall feeling of a mess compared to 2007 in Shanghai auto show I heard the call on Hu Maoyuan South cooperation, which is a strange signal, until the Guangzhou Motor Show, Shao Huiqi premature criticism of China's automobile, together with a common, all that I felt puzzled.
often do have a lot of things sub-sequence as I breathe out in the original forest, when, and occasionally into the team ����ԽҰ�� see, they are military vehicles. but I came out, I see the country on the text SUV prospects for the future, I do not want to admit it, through the Typhoon several times, car repair and service company, is said to have an amendment to change from the SUV and pickup cars.
Anhai take a trip in Shanghai, 825 trams, Shanghai Electric electric hybrid car the first public transport operator 825 Road and the opening lines are epoch-making significance. electric electric hybrid vehicles in addition to fuel cars with features, it does not fuel the engine noise. The success of the Shanghai Science and Technology Electric Power company, which is based on the structure of capacitor and battery-powered hybrid car. Shanghai Science and Technology Center Director Yu Guoqin Power Company that it is a revolutionary means of transport, with independent intellectual property rights, in the near future will replace the fuel public transport vehicles. Therefore, I wrote an article with BYD iron battery to support the article.
Overall, the automotive sector in China in 2007, less than last week Tiger, in addition to the oil stir the hearts of everyone, there is brewing a full of evil tax uncertainties. Oh, the auto market this year, the tide is definitely a big price cut scene, as in previous years, car makers have employed propaganda, saying that no two drop down a printing of said Shang Dangzhe: car dealer if you believe that? Therefore, this year is the price of a boring in the end. but also the close, the era of profiteering in China is about gone, and silence cut prices eventually dropped to the lowest price than foreign equivalent models. < br> I experienced the car in the event of 2007 is not much, I still fragmentary personal experience, but too small debris, and I think as long as skyrocketing oil is not cramps, Chinese cars in 2008, is still bright, but it may is in the public, rather than in general. to take this machine, I have asked the Beijing Olympic Organizing Committee soon, why not launch its own car? Olympic Games Men's government used tax money, there is no reason not to let anyone know. Beijing Olympic Committee, the money really that important to you?
Gu Qingsheng
2007 spring one from the south to Beijing, I went to find a common drink PR, I thought it was a Banquet, it, too. Why GM public relations I find it? An Xiang mainly because I wrote a piece on the car, in Back in 2007, when I played this piece in particular memory. as follows:
in China within a large valley, a detour to a new car parts, sun shining, shimmering metallic sheen. It does not know who the owner, I do not know ancient or modern, I do not know is the earth, or aliens, in short, I do not know to place. One day, Germany people playing here before, peruse, pick out the demolition of refined automotive wrench away, about his lack of such a wrench kit. Then came one of the Japanese, the Japanese took out pen and paper, the zero Parts painted it again, take nothing, go back to the repairer according to the drawings. after the arrival of the Chinese people as the Japanese, quickly took out the camera while Kuangpai, and then get the magazine to express: I national archaeological discoveries have , Prehistoric Men will repairer, and there are auto parts to prove it. the Americans finally came and looked at, the estimated model can be fitted into a good car, begins with the foot shouting come and spend money that they would spare parts loaded into a car, a Buick trademark black of the paste, it becomes a Buick or Chevrolet car, place to sell a good price.
I stop writing this piece, and my heart has always been very satisfied General public relations may not think of this dissatisfaction, there is no poetry in an era, people like to read fables, at best, only said that Americans are business-minded than other people, GM is also so fragile? drink to half of the general public relations go, I left one child to drink slowly. He said he was busy, I is not busy, I was working on the school, Lin Hui from the Zhongguancun Tongzhou drink a month for Han Hao.
words on to the Shanghai auto show, I also spent half a hurry will go to Chongqing Book Fair. after four months did not care about cars, virgin forests and Tibetan Plateau not the Internet. Simply put, I like the car in 2007 from farther away. Fortunately, back to Beijing, found the Chinese auto elite group, the QQ chat group every day cars, I have been told I look for wheat to a 212, the process to such a more.
addition, Anhai found the car features three cities, Chengdu is a city car the most complex, from the Alto to the Audi, what series of cars slowly walking in the streets. Gein Chengdu, free and easy consumer concept, to consume what car to buy cars, and will not tiptoe to buy luxury cars filling wide, I think that is the wisdom of the people of Chengdu. But to go to Shenyang, I often go to a decade ago, when the streets to do in Shenyang running head soil soil refuse of the brain, and now many of the streets ran dry frog simmer Hash General Audi. Yangzhou other information is received, the city's private cars accounted for 40%, which is the largest city with private cars . because in Yangzhou, a private car can also be put into operation, is a tourist city of Yangzhou, 24, no bridge, then swam around the Slender West Lake.
words to say to the front of the piece, in fact, Asian countries it is the general mentality of people . After all general dissatisfaction, it may care about OEM, but OEM Anjiu see GM Wuling, ditch in the mountains, there are many, it does hold up a common sales performance. In addition, I at least In the four provinces take the general business class. I feel that GM might sell a good business position, as well as GM-Wuling sold well, a bit Daya and vulgar taste. this comparison, I also towards national brands shift in this direction, while mid-range sprint cars, while maintaining the manufacturing economy.
I ordered the country is developing its own brand in the state, the first half of the automobile market through the stock market sun shone nice and warm, in the second half with the stock market's ups and downs, the automobile market there panic-type sell-off, the storm has arrived. In this period, particularly oil rising to 10% of the benchmark, the general impact of such enterprises will certainly be. And the slowdown in the market its own brand, I that the benefit of its own brand, be it 10 minutes out of a car assembly line, you can put out one to 20 minutes, and that work will seem fine than before.
overall feeling of a mess compared to 2007 in Shanghai auto show I heard the call on Hu Maoyuan South cooperation, which is a strange signal, until the Guangzhou Motor Show, Shao Huiqi premature criticism of China's automobile, together with a common, all that I felt puzzled.
often do have a lot of things sub-sequence as I breathe out in the original forest, when, and occasionally into the team ����ԽҰ�� see, they are military vehicles. but I came out, I see the country on the text SUV prospects for the future, I do not want to admit it, through the Typhoon several times, car repair and service company, is said to have an amendment to change from the SUV and pickup cars.
Anhai take a trip in Shanghai, 825 trams, Shanghai Electric electric hybrid car the first public transport operator 825 Road and the opening lines are epoch-making significance. electric electric hybrid vehicles in addition to fuel cars with features, it does not fuel the engine noise. The success of the Shanghai Science and Technology Electric Power company, which is based on the structure of capacitor and battery-powered hybrid car. Shanghai Science and Technology Center Director Yu Guoqin Power Company that it is a revolutionary means of transport, with independent intellectual property rights, in the near future will replace the fuel public transport vehicles. Therefore, I wrote an article with BYD iron battery to support the article.
Overall, the automotive sector in China in 2007, less than last week Tiger, in addition to the oil stir the hearts of everyone, there is brewing a full of evil tax uncertainties. Oh, the auto market this year, the tide is definitely a big price cut scene, as in previous years, car makers have employed propaganda, saying that no two drop down a printing of said Shang Dangzhe: car dealer if you believe that? Therefore, this year is the price of a boring in the end. but also the close, the era of profiteering in China is about gone, and silence cut prices eventually dropped to the lowest price than foreign equivalent models. < br> I experienced the car in the event of 2007 is not much, I still fragmentary personal experience, but too small debris, and I think as long as skyrocketing oil is not cramps, Chinese cars in 2008, is still bright, but it may is in the public, rather than in general. to take this machine, I have asked the Beijing Olympic Organizing Committee soon, why not launch its own car? Olympic Games Men's government used tax money, there is no reason not to let anyone know. Beijing Olympic Committee, the money really that important to you?
Thursday, February 17, 2011
Wedding anniversary
Today is my wedding anniversary and Dani
sixteen years of our published a new book, named for the expedition for the new book, love so deep! so put! we withstood all the pressures, including relatives of people do not understand the rejection, we duty-bound us hand in hand, and now I'm still kind of situation as the out of control, I will miss you, like Like the little girl crying, worried about your first love, I would like it, put a love letter I wrote you letters sent to you. think of so many years, our love is this how if Burongyia ! use your words, know that we process the 16-year period, they saw only the present results. but 16 years we have experienced difficult process, it is the witness of our love for each other. I often thought about these processes, in which a recall of I got a lot of comfort. I enjoy the process, this also inspired me to enjoy my love more love, more love we have for this family. and our efforts to our struggle, is not it precisely to our small family life, you had better and more fulfilling!
Yesterday we the.
Danielle wrote in 2009 of our anniversary
sixteen years of our published a new book, named for the expedition for the new book, love so deep! so put! we withstood all the pressures, including relatives of people do not understand the rejection, we duty-bound us hand in hand, and now I'm still kind of situation as the out of control, I will miss you, like Like the little girl crying, worried about your first love, I would like it, put a love letter I wrote you letters sent to you. think of so many years, our love is this how if Burongyia ! use your words, know that we process the 16-year period, they saw only the present results. but 16 years we have experienced difficult process, it is the witness of our love for each other. I often thought about these processes, in which a recall of I got a lot of comfort. I enjoy the process, this also inspired me to enjoy my love more love, more love we have for this family. and our efforts to our struggle, is not it precisely to our small family life, you had better and more fulfilling!
Yesterday we the.
Danielle wrote in 2009 of our anniversary
Wednesday, February 16, 2011
1 year 10 million demand deposits,
10 demand deposits 1 year pocketbook. China's CPI rise in January was 4.9%. By this calculation, Kunming, how much revenue a year from the deposits it? CPI rose 4.9%, Lump Fixed interest rate of 3.0% a year, what is this concept? It means that negative interest rates widened to 1.9%, which means the 10 million people in the bank after one year equivalent to the current 95,100 yuan can only buy the goods, even if interest rates are on a regular basis with 3,000 a year , it was also loss of 1,900 yuan.
deposit 10 million loss compared to 1900 yuan, current savings afford to lose even more. The demand deposit interest rate is only 0.4%, equivalent to 10 million in current savings, the actual loss of 4,500 yuan.
bank financial experts for our calculations: deposit rate minus the CPI, the result is that the real value of deposits. Higher than CPI due to the current deposit interest rates, negative interest rates has become a year down the deposit. Lump Fixed interest rate of the current year was 3.0%, which means widening negative interest rates to 1.9%, which means the 1 million to the bank, only to buy after one year equivalent to the current 9,510 yuan in goods, together with interest on time deposits 300 per year, or the loss of 190 million. That the higher CPI, the more deflated people's pocketbook.
1 loss of 190 yuan deposits, current savings is fortunately more. Now the demand deposits of 0.4% per annum, equivalent to 1 million in current savings, a year down the actual loss 450.
Yunnan University Professor Hu Qihui said that, judging from the figures this year, inflationary pressures remain, and even more can be said that big. CPI in December last year, largely because of falling levels of government intervention in the role of the CPI in January this year, is high after a new wave of price Nan Yi rebound. Monetary easing policy in developed countries may have to run through this year, international commodity prices in general tend to rise; domestic currency over the past two years the mobility of relaxed hair is currently being conducted in inflationary pressures and, most importantly in the next few years will existing labor and land costs, the objective of this series of factors there has been, in fact, the year 2011, CPI may reach 5% -6%. In contrast, in the future to several consecutive interest rate increase of 0.25% is nothing.
preganglionic
Kunming average wholesale price of vegetables rose 10%
Jun Meng reporters before and after the Spring Festival Prices rose an average 10% longer than usual, has been restored to pre-holiday levels. Wang Qi camp vegetable wholesale market, cabbage prices from the 7 corner during the Spring Festival / kg to 5 angle. In addition, fruit, pork prices also rose during the Spring Festival.
yesterday, Wang Qi camps within the wholesale vegetable market vegetable prices displayed, tomatoes 2.5 yuan / kg, green pepper 4 yuan / kg over 1 yuan during the Spring Festival of decline. According to Wang Qi Trading Co., Ltd. vegetable wholesale business marketing director Li Kunpeng introduced, prices of vegetables each year will rise during the Spring Festival this year rose an average of about 10%, the high lasted for 20 days around the Spring Festival. the formation of the imbalance between supply and demand prices.
farmers market vegetable prices also declined. The price of a small melon preganglionic 4-5 yuan / kg, now 2.5-3 Yuan / kg, generally declined. White Dragon Temple farmers markets, pork prices also gained during the Spring Festival.
addition, wood spray before the Spring Festival comprehensive broad based market price of fruit, small mandarin orange from the previous 6-8 yuan / kg rose to 13-17 yuan / kg, Shandong Fuji from 8 yuan / kg rose to 12.8 yuan / kg, navel orange from 4 yuan / kg rose to 7 yuan / kg, current prices remain high.
Festival of rice rose slightly
reporters yesterday from the pavilion Qincong Jun grain wholesale market and multi-grain and oil market Wuli was informed by some of the shops after the Spring Festival, Kunming, a slight increase of rice, of which Royal tribute from the Northeast long grain fragrant, good snow, and the Songhua River Zhenzhu Mi Akita Komachi prices have gone up before the holiday from 0.1 to 0.3 yuan. Which the largest increase from Maitreya and other places fragrant rice, most of them have risen by 1 million.
Ze from merchants Miss Choi will introduce long-grain as the Royal Hong Gong preganglionic 4.65 yuan / kg, after the holiday is 4.75 yuan / kg; a Yiliang business description, Maitreya rice festival the former is 6 yuan / kg, after the holiday was 6.6 yuan / kg. Rice flower come from the Northeast was up by 1 million, before the holiday is 6 yuan / kg, after the holiday is 7 yuan / kg.
causes rice prices, traders said, by the impact of other price increases, after the holiday rice markets rose slightly different degrees, on average, rice, rose after the holiday in the 0.3 yuan / kg .
rising CPI so that the public learned of reckoning Xinhua
have countermeasures
money to eat in school aged young people do not plan carefully cooking
price pressures in the future still exist, how rational arrangement consumption, lower cost of living, increase property income, has become a lot of people can not avoid the issue.
National Bureau of Statistics released in January after the end of the 50 cities the average price changes in major food data, 29 species of food prices declined slightly in addition to individual species, the vast majority of species prices continue to rise.
In fact, these figures had generally boring concrete into the daily lives of ordinary people, the most intuitive feeling is from the to the
50-year-old Miss Song Ping Jinan residents CPI a few years ago I do not know what that is, but it experienced in 2010, she already knew as long as the CPI rose, it means less and less money in pocket The flowers.
Moreover, some from the strong spending power of young people that also reduced their prices in front of A foreign trade company in Qingdao, said Liu Jie, the work of the past are eating out, so to save trouble, but the number of times since last year at home cooking up more, eating out too expensive, such as most like to eat spicy chicken, last 18 yuan, rose to 20 per year, and now risen to 22 yuan. Do not underestimate the learning to cook, not to save money, said the instructions on the recipes can make you more healthy.
reporter learned that, faced with the current price pressures, many people have begun to pay attention to the formation of life science, consumer habits. Some netizens joke, if the price rises to a certain extent, Xinhua News Agency
financial investment index fund and a good choice of silver or
reporter Liao Zhiguo gradual decline, 'negative interest rates' will continue for more than a quarter of the time. 'The central bank in a few short-term bank deposit rates in the experimental market' press release, indicating the market deposit rates or actual action, while the current interest rate cycle, people do not simply put money in the bank.
, Andy standard that, first of all if the rate hike, the people have dumped trouble; followed by At present, the annual number of financial products over a year time deposit rate of return of 3% interest, this is a good choice. Overall, the public can choose their own risk tolerance, investment preferences, select the higher income than the market of financial products. to a wave of bull market within two years, this year's main stock index to at least 3000 points to stand at the top. Because silver investment participation threshold is low, with the increasing number of investment, price volatility will be greater, and if T + D silver can be two-way trading, silver prices fall can make money.
midline stock market emerged in February and March or between
reporter Liao Zhiguo slightly Stock Index opened higher yesterday after the oscillations increase. The morning of January 10 announced lower than expected economic data, lower market concerns about inflation, not a shock to the index. Main stock index touched 2934 points once the afternoon, but some sort of relief drive down stock sell-off caused by the final 2900 point integer failed to pass a firm, K line to close out a long upper shadow. Slightly enlarged volume between the two cities.
GF Securities analyst Xu Jun Kunming business department that the stock index rebounded from a 2661 point increase has been 10%, there is also finished lower short-term is normal. Technically, the stock index point is pre-2930 high platform, multi-consolidation of power need to digest before they can break off. Or continue to maintain the pre-holiday on the Investors are advised not to chase the high pre-hot plate, for a prolonged slump in the stock price can focus.
Cinda Fund investment strategy report in 2011 that the stock market this year to tighten money supply in case of difficult to have a large market. The logic behind that is: the market valuation determined by the liquidity in the case of tight liquidity, the central valuation down, the market rose only by profit-driven, profitable growth and space is limited, so price is a high degree of limited. On the other hand, the overall market valuation and relatively cheap, thus limiting the market's fall. Are likely to remain box stock index oscillation pattern, about 20% based on earnings growth expectations, the cabinet also highly estimated 20% to 30% range. Investors are advised to adopt a strategy of active defense. Speaking from the position, the market if the increase (20%), can lighten up to the base under consideration; if the market falls (20%), consider Masukura to the reference above. From the stock of structure, not just selected growth, choosing instead to underestimate the value added growth for defense, get rid of all the apparently high valuation of the stock.
deposit 10 million loss compared to 1900 yuan, current savings afford to lose even more. The demand deposit interest rate is only 0.4%, equivalent to 10 million in current savings, the actual loss of 4,500 yuan.
bank financial experts for our calculations: deposit rate minus the CPI, the result is that the real value of deposits. Higher than CPI due to the current deposit interest rates, negative interest rates has become a year down the deposit. Lump Fixed interest rate of the current year was 3.0%, which means widening negative interest rates to 1.9%, which means the 1 million to the bank, only to buy after one year equivalent to the current 9,510 yuan in goods, together with interest on time deposits 300 per year, or the loss of 190 million. That the higher CPI, the more deflated people's pocketbook.
1 loss of 190 yuan deposits, current savings is fortunately more. Now the demand deposits of 0.4% per annum, equivalent to 1 million in current savings, a year down the actual loss 450.
Yunnan University Professor Hu Qihui said that, judging from the figures this year, inflationary pressures remain, and even more can be said that big. CPI in December last year, largely because of falling levels of government intervention in the role of the CPI in January this year, is high after a new wave of price Nan Yi rebound. Monetary easing policy in developed countries may have to run through this year, international commodity prices in general tend to rise; domestic currency over the past two years the mobility of relaxed hair is currently being conducted in inflationary pressures and, most importantly in the next few years will existing labor and land costs, the objective of this series of factors there has been, in fact, the year 2011, CPI may reach 5% -6%. In contrast, in the future to several consecutive interest rate increase of 0.25% is nothing.
preganglionic
Kunming average wholesale price of vegetables rose 10%
Jun Meng reporters before and after the Spring Festival Prices rose an average 10% longer than usual, has been restored to pre-holiday levels. Wang Qi camp vegetable wholesale market, cabbage prices from the 7 corner during the Spring Festival / kg to 5 angle. In addition, fruit, pork prices also rose during the Spring Festival.
yesterday, Wang Qi camps within the wholesale vegetable market vegetable prices displayed, tomatoes 2.5 yuan / kg, green pepper 4 yuan / kg over 1 yuan during the Spring Festival of decline. According to Wang Qi Trading Co., Ltd. vegetable wholesale business marketing director Li Kunpeng introduced, prices of vegetables each year will rise during the Spring Festival this year rose an average of about 10%, the high lasted for 20 days around the Spring Festival. the formation of the imbalance between supply and demand prices.
farmers market vegetable prices also declined. The price of a small melon preganglionic 4-5 yuan / kg, now 2.5-3 Yuan / kg, generally declined. White Dragon Temple farmers markets, pork prices also gained during the Spring Festival.
addition, wood spray before the Spring Festival comprehensive broad based market price of fruit, small mandarin orange from the previous 6-8 yuan / kg rose to 13-17 yuan / kg, Shandong Fuji from 8 yuan / kg rose to 12.8 yuan / kg, navel orange from 4 yuan / kg rose to 7 yuan / kg, current prices remain high.
Festival of rice rose slightly
reporters yesterday from the pavilion Qincong Jun grain wholesale market and multi-grain and oil market Wuli was informed by some of the shops after the Spring Festival, Kunming, a slight increase of rice, of which Royal tribute from the Northeast long grain fragrant, good snow, and the Songhua River Zhenzhu Mi Akita Komachi prices have gone up before the holiday from 0.1 to 0.3 yuan. Which the largest increase from Maitreya and other places fragrant rice, most of them have risen by 1 million.
Ze from merchants Miss Choi will introduce long-grain as the Royal Hong Gong preganglionic 4.65 yuan / kg, after the holiday is 4.75 yuan / kg; a Yiliang business description, Maitreya rice festival the former is 6 yuan / kg, after the holiday was 6.6 yuan / kg. Rice flower come from the Northeast was up by 1 million, before the holiday is 6 yuan / kg, after the holiday is 7 yuan / kg.
causes rice prices, traders said, by the impact of other price increases, after the holiday rice markets rose slightly different degrees, on average, rice, rose after the holiday in the 0.3 yuan / kg .
rising CPI so that the public learned of reckoning Xinhua
have countermeasures
money to eat in school aged young people do not plan carefully cooking
price pressures in the future still exist, how rational arrangement consumption, lower cost of living, increase property income, has become a lot of people can not avoid the issue.
National Bureau of Statistics released in January after the end of the 50 cities the average price changes in major food data, 29 species of food prices declined slightly in addition to individual species, the vast majority of species prices continue to rise.
In fact, these figures had generally boring concrete into the daily lives of ordinary people, the most intuitive feeling is from the to the
50-year-old Miss Song Ping Jinan residents CPI a few years ago I do not know what that is, but it experienced in 2010, she already knew as long as the CPI rose, it means less and less money in pocket The flowers.
Moreover, some from the strong spending power of young people that also reduced their prices in front of A foreign trade company in Qingdao, said Liu Jie, the work of the past are eating out, so to save trouble, but the number of times since last year at home cooking up more, eating out too expensive, such as most like to eat spicy chicken, last 18 yuan, rose to 20 per year, and now risen to 22 yuan. Do not underestimate the learning to cook, not to save money, said the instructions on the recipes can make you more healthy.
reporter learned that, faced with the current price pressures, many people have begun to pay attention to the formation of life science, consumer habits. Some netizens joke, if the price rises to a certain extent, Xinhua News Agency
financial investment index fund and a good choice of silver or
reporter Liao Zhiguo gradual decline, 'negative interest rates' will continue for more than a quarter of the time. 'The central bank in a few short-term bank deposit rates in the experimental market' press release, indicating the market deposit rates or actual action, while the current interest rate cycle, people do not simply put money in the bank.
, Andy standard that, first of all if the rate hike, the people have dumped trouble; followed by At present, the annual number of financial products over a year time deposit rate of return of 3% interest, this is a good choice. Overall, the public can choose their own risk tolerance, investment preferences, select the higher income than the market of financial products. to a wave of bull market within two years, this year's main stock index to at least 3000 points to stand at the top. Because silver investment participation threshold is low, with the increasing number of investment, price volatility will be greater, and if T + D silver can be two-way trading, silver prices fall can make money.
midline stock market emerged in February and March or between
reporter Liao Zhiguo slightly Stock Index opened higher yesterday after the oscillations increase. The morning of January 10 announced lower than expected economic data, lower market concerns about inflation, not a shock to the index. Main stock index touched 2934 points once the afternoon, but some sort of relief drive down stock sell-off caused by the final 2900 point integer failed to pass a firm, K line to close out a long upper shadow. Slightly enlarged volume between the two cities.
GF Securities analyst Xu Jun Kunming business department that the stock index rebounded from a 2661 point increase has been 10%, there is also finished lower short-term is normal. Technically, the stock index point is pre-2930 high platform, multi-consolidation of power need to digest before they can break off. Or continue to maintain the pre-holiday on the Investors are advised not to chase the high pre-hot plate, for a prolonged slump in the stock price can focus.
Cinda Fund investment strategy report in 2011 that the stock market this year to tighten money supply in case of difficult to have a large market. The logic behind that is: the market valuation determined by the liquidity in the case of tight liquidity, the central valuation down, the market rose only by profit-driven, profitable growth and space is limited, so price is a high degree of limited. On the other hand, the overall market valuation and relatively cheap, thus limiting the market's fall. Are likely to remain box stock index oscillation pattern, about 20% based on earnings growth expectations, the cabinet also highly estimated 20% to 30% range. Investors are advised to adopt a strategy of active defense. Speaking from the position, the market if the increase (20%), can lighten up to the base under consideration; if the market falls (20%), consider Masukura to the reference above. From the stock of structure, not just selected growth, choosing instead to underestimate the value added growth for defense, get rid of all the apparently high valuation of the stock.
Tuesday, February 15, 2011
Who is more noble and qing Miaoyu
Interpretation of gem So in the end is in trouble Miaoyu princess or an ordinary nun? qing in the end is a hidden princess? was a to the right?
first look qing.
Indeed, in the fifth round, the qing wrote many great room furniture, see also dazzling gem, indeed like a princess room. So there qing the possibility that the princess. Liu Xinwu is fascinated by these images, is the princess of the mistake qing. that Ping Ziying Zhang imperial doctor also introduced to so believe.
look at Miaoyu.
live in the temple of There are also many of the world Miaoyu rare treasures. Granny Liu binary Grand View Garden, when Lady Dowager to bring everyone into the cozy sit Tsui Temple, Miaoyu then took out his own tea. this time we have seen, this band Fat girl practice, out of tea, no one is not rare in the world's treasures. She even confidently exclaimed: most people will have confidence in you?
qing have such confidence in it? qing such a manner it? can not see! do not see a princess in any manner qing. She has not princess grace, they can even serve gem sleep (see the fifth round). (As for why let her sleep mm gem serving explain later) that where the identity like a princess?
and Miaoyu is different. her in the face of the highest Jia Grandmother Jia leaders, too, showed neither haughty nor humble attitude, that has not lost to the tone of Jia. not a princess, but where such a temperament? would be no such confidence? where would such a noble?
Grandmother Jia said, .
, of course, this sentence there is also additional information, who read it?
Miaoyu into the Grand View Garden is Mrs. Wang took invitations invited her, but when Mrs. Wang, Xue Yima followed came in the back of Jia, Miaoyu even tea did not give them back, she brought the tea is just tea, a person of Jia. In other words, just trying to do the most simple courtesy. it can be said, played Miaoyu is only installed for show. Then, no matter what she had they simply and Tai-yu and Bao Chai, gem to the tea. their tea in which four people, a lot of time, because she put the water boil. In Bao Dai and others in which such tea to drink when the Lady Dowager, Lady Wang, Xue Yima rest on the outside. Miaoyu eat in the living Jia Jia, dare so proudly, the capital that? < br> into the kiln cover small colorful tea valuable, just because they were Granny Liu drank tea, Miaoyu do not, this is the princess style home! of tea not only wrote about the tea Jia Mu , Tai-yu and Bao Chai, gem of these three tea tea, and even wrote about the tea cup of tea Zhongjie Mei mm porcelain studies have friends, can you tell me the On the origin of specifically highlighted in the tea, not just to tell us, even to the people drinking tea tea, Miaoyu out nor is the public goods!
qing die, Zhen Jia to give her to find a pay good wood coffin, Jia Zheng said, and that the coffin princess; just a stunt, stuntman Princess.
and Miaoyu is the princess.
Miaoyu princess mm So, this is the
first look qing.
Indeed, in the fifth round, the qing wrote many great room furniture, see also dazzling gem, indeed like a princess room. So there qing the possibility that the princess. Liu Xinwu is fascinated by these images, is the princess of the mistake qing. that Ping Ziying Zhang imperial doctor also introduced to so believe.
look at Miaoyu.
live in the temple of There are also many of the world Miaoyu rare treasures. Granny Liu binary Grand View Garden, when Lady Dowager to bring everyone into the cozy sit Tsui Temple, Miaoyu then took out his own tea. this time we have seen, this band Fat girl practice, out of tea, no one is not rare in the world's treasures. She even confidently exclaimed: most people will have confidence in you?
qing have such confidence in it? qing such a manner it? can not see! do not see a princess in any manner qing. She has not princess grace, they can even serve gem sleep (see the fifth round). (As for why let her sleep mm gem serving explain later) that where the identity like a princess?
and Miaoyu is different. her in the face of the highest Jia Grandmother Jia leaders, too, showed neither haughty nor humble attitude, that has not lost to the tone of Jia. not a princess, but where such a temperament? would be no such confidence? where would such a noble?
Grandmother Jia said, .
, of course, this sentence there is also additional information, who read it?
Miaoyu into the Grand View Garden is Mrs. Wang took invitations invited her, but when Mrs. Wang, Xue Yima followed came in the back of Jia, Miaoyu even tea did not give them back, she brought the tea is just tea, a person of Jia. In other words, just trying to do the most simple courtesy. it can be said, played Miaoyu is only installed for show. Then, no matter what she had they simply and Tai-yu and Bao Chai, gem to the tea. their tea in which four people, a lot of time, because she put the water boil. In Bao Dai and others in which such tea to drink when the Lady Dowager, Lady Wang, Xue Yima rest on the outside. Miaoyu eat in the living Jia Jia, dare so proudly, the capital that? < br> into the kiln cover small colorful tea valuable, just because they were Granny Liu drank tea, Miaoyu do not, this is the princess style home! of tea not only wrote about the tea Jia Mu , Tai-yu and Bao Chai, gem of these three tea tea, and even wrote about the tea cup of tea Zhongjie Mei mm porcelain studies have friends, can you tell me the On the origin of specifically highlighted in the tea, not just to tell us, even to the people drinking tea tea, Miaoyu out nor is the public goods!
qing die, Zhen Jia to give her to find a pay good wood coffin, Jia Zheng said, and that the coffin princess; just a stunt, stuntman Princess.
and Miaoyu is the princess.
Miaoyu princess mm So, this is the
Monday, February 14, 2011
Confused wait
Confusion, a beautiful little compassion words
life like a dream, both real and unreal
and I like a vagrant soul, no direction
shop in the air scatter sunlight , lazy but warm
I stand in the crowd quietly into the air close to the
result, pedestrians hurried quietly into the background
I stopped at that
like a lost child, butter, waiting for what
but he is not scared I just stood
not anxious, lazy warmth of the sun dropped into the bottom of my heart
even very calm, waiting for something ...... I Not sure, but always waiting for the arrival of
waiting for you, waiting for your voice
waiting for you even if only the word only language film is a mood
waiting for her inner feelings A world where everyone has the desire
waiting for love waiting, waiting for the joy of success
waiting, waiting for our mutual happiness
just a different mood each time waiting for the time
heart kind of sense of joy and loss
life like a dream, both real and unreal
and I like a vagrant soul, no direction
shop in the air scatter sunlight , lazy but warm
I stand in the crowd quietly into the air close to the
result, pedestrians hurried quietly into the background
I stopped at that
like a lost child, butter, waiting for what
but he is not scared I just stood
not anxious, lazy warmth of the sun dropped into the bottom of my heart
even very calm, waiting for something ...... I Not sure, but always waiting for the arrival of
waiting for you, waiting for your voice
waiting for you even if only the word only language film is a mood
waiting for her inner feelings A world where everyone has the desire
waiting for love waiting, waiting for the joy of success
waiting, waiting for our mutual happiness
just a different mood each time waiting for the time
heart kind of sense of joy and loss
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